Talk:Sharpless epoxidation

It's unclear to me what determines the entatioselectivity of the reaction. Can someone clarify that a bit? Even from his article on Organic Syntheses, I can't seem to make it out. He's producing a 2S, 3S product, but can you produce a 2R, 3R product and if so, how?

It's the asymmetric environment of the diethyl tartrate. I'll try to build on this article soon. ~K 20:00, 26 November 2006 (UTC)[reply]

Wow! Thanks for the nearly instantaneous response. And sorry for not signing my previous post. I suspected it was the DET but I wasn't sure. -- Pdavis68 20:02, 26 November 2006 (UTC)[reply]

The diagram here is incorrect. The "wedge" version is actually produced by (-)-DET, not (+)-DET.

No, it is not. Though it seems to contradict the L (-)-DET equals L ower face mnemonic, it does not because the educt allylic alcohol is NOT drawn in the way for the mnemonic to be used.

Katsuki anyone?!

This is often referred to as the Sharpless-Katsuki epoxidation, and I think Katsuki deserves a mention at least! Seansheep 15:41, 4 December 2007 (UTC)[reply]

Question

When actually did sharpless publish his work on epoxidation reaction??? 105.58.212.96 (talk) 14:32, 6 March 2023 (UTC)[reply]